IDWeek Poster にASP関連は多数あります。最近、結果に興味があるので以下をピックアップ。 Antimicrobial Stewardship: Interventions to Improve Outcomes https://idsa.confex.com/idsa/2018/webprogram/Session10451.html

2018-09-26

Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia A Randomized Clinical Trial

JAMA RCT ASP Adverse Events Bundle

JAMAに報告された、Staphylococcal Bacteremiaに対するアルゴリズム。 https://jamanetwork.com/journals/jama/fullarticle/2703352

2018-09-20

Validation of an Antimicrobial Stewardship Driven Verigene® Blood-Culture Gram-Negative Treatment Algorithm to Improve Appropriateness of Antibiotics

ASP Antibiotic resistance AI De-escalation OFID

OFIDに報告された、RDTを組み込んだ血液培養グラム陰性治療アルゴリズムの検証 academic.oup.com

2018-09-13

Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance

JAMA RCT Antibiotic resistance ASP

JAMAに報告された、いわゆるESBL産生大腸菌・肺炎桿菌菌血症に対する、RCT/非劣勢。MERINO trial https://jamanetwork.com/journals/jama/fullarticle/2702145

2018-09-11

Principles of antimicrobial therapy of Pseudomonas aeruginosa infections

Antibiotic resistance ASP Combination therapy

緑膿菌に対する抗菌薬について、学校講義始まるので UP To Date で復習

2018-08-26

某シンポジウムで引用した論文

ASP Others Adverse Events Antibiotic resistance

シンポジウム楽しめました。他シンポジストの発表から刺激をいただきました。ありがとうございました！私が引用した論文一覧

2018-08-19

The ID Pharmacist’s Critical Role in Improving Patient Outcomes: Dr. Paul Sax Interviews Dr. Susan Davis

ASP OFID

SIDP のPodcast文字起こし。 ID pharmacistに関する、興味深い対談でした。 academic.oup.com

2018-08-16

A PrEP model incorporating clinical pharmacist encounters and antimicrobial stewardship program oversight may improve retention in care

ASP HIV Clin Infect Dis

CIDから、薬剤師をPrEPモデルに組み込んだ報告 academic.oup.com

2018-08-15

Impact of Implementing Antibiotic Stewardship Programs in 15 Small Hospitals: A Cluster-Randomized Intervention

ASP Clin Infect Dis

CDIに報告された、小規模病院ASPの Cluster-Randomized Intervention www.ncbi.nlm.nih.gov

2018-08-14

Impact of an emergency medicine pharmacist on empiric antibiotic prescribing for pneumonia and intra-abdominal infections.

Pharmacist-driven antimicrobial stewardship ASP

肺炎と腹腔内感染に対する、emergency medicine pharmacistのインパクト www.ncbi.nlm.nih.gov

2018-08-13

Impact of matrix-assisted laser desorption/ionization time of flight mass spectrometric evaluation on the clinical outcomes of patients with bacteremia and fungemia in clinical settings lacking an antimicrobial stewardship program: a pre-post quasi experi

ASP

BMC Inf Dis から、MALDI-TOF MSの臨床インパクト報告 www.ncbi.nlm.nih.gov

2018-08-06

Onset of symptoms, diagnostic confirmation, and occurrence of multiple infective foci in patients with Staphylococcus aureus bloodstream infection: a look into the order of events and potential clinical implications.

ASP

Staphylococcus aureus菌血症 : CVC、VO、IE に関する報告 www.ncbi.nlm.nih.gov

2018-07-30

De-escalation and discontinuation strategies in high-risk neutropenic patients: an interrupted time series analyses of antimicrobial consumption and impact on outcome.

ASP FN

Eur J Clin Microbiol Infect Dis に報告された、好中球減少患者に対する、De-escalation and Discontinuation 戦略。 www.ncbi.nlm.nih.gov

2018-07-15

What is antimicrobial stewardship?

ASP

2017年CMIから報告された、"What is antimicrobial stewardship?" www.ncbi.nlm.nih.gov

2018-07-12

Antimicrobial Stewardship and Intensive Care Unit (ICU) Mortality: A systematic review.

ASP Clin Infect Dis Systematic Review and Meta-analysis

CIDからの報告。ASPとICUの死亡率について、11研究からのレビュー。 www.ncbi.nlm.nih.gov

2018-07-10

'Careful goodbye at the door': is there role for antimicrobial stewardship interventions for antimicrobial therapy prescribed on hospital discharge?

ASP

2018年にBMC Inf Disから報告された、ASP論文。 www.ncbi.nlm.nih.gov

2018-07-08

Impact of an antimicrobial stewardship program on outcomes in patients with community-acquired pneumonia admitted to a tertiary community hospital.

ASP

シンポジウムに向けてASPをしばし復習します。 2018年 ashpから報告された、ASP www.ncbi.nlm.nih.gov

2018-01-22

Effectiveness of an Antimicrobial Stewardship Program in Critical Care: A Before-and-After Study.

ASP

AACに発表された、バロセロナにある総合病院のICUによるASPの効果。

2017-12-07

Efficacy and safety of delafloxacin compared with vancomycin plus aztreonam for acute bacterial skin and skin structure infections: a Phase 3, double-blind, randomized study

ASP RCT Phases3

JACに報告された、皮膚感染に対する、delafloxacin vs vancomycin plus aztreonamのP3。 academic.oup.com

2017-12-06

Daptomycin treatment in patients with resistant staphylococcal periprosthetic joint infection.

ASP

BMC ID に発表された、人工関節周囲感染に関するDPTレトロ。 DPT 8.3mg/kg 高用量使用していました。 BMC IDは査読過程も確認できるので、好きな雑誌です。 bmcinfectdis.biomedcentral.com

2017-11-25

Hospital antimicrobial stewardship: the way forward

ASP Lancet Systematic Review and Meta-analysis Clostridioides difficile infection

LIDで発表された Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis http://www.thelancet.com/journals…

2017-11-08

Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials

ASP Lancet Continuous infusion Systematic Review and Meta-analysis

LIDに発表された、抗緑膿菌ベータラクタム系薬の持続投与に関するメタアナ。 http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(17)30615-1/fulltext

2017-11-06

Empiric Therapy With Carbapenem-Sparing Regimens for Bloodstream Infections due to Extended-Spectrum β-Lactamase–Producing Enterobacteriaceae: Results From the INCREMENT Cohort

ASP Clin Infect Dis Lancet

CIDに報告された、ESBL産生菌に対するエンピリック療法に関する内容。元データは、INCREMENTコホート研究 (Lancet Infect Dis. 2017 Jul;17(7):726-734. )。

2017-11-03

Impact of requiring re-authorization of restricted antibiotics on day 3 of therapy.

ASP

JACに報告された、抗菌薬治療3日目の抗菌薬使用制限に関する検討。

2017-11-02

Procalcitonin and antibiotic use: imperfect, yet effective

ASP Lancet Biomarker-guided：procalcitonin etc

LIDに報告された、プロカルチンと抗菌薬についてのコメント http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(17)30593-5/fulltext

3児の親さん薬剤師のブログ

とある薬剤師です。感染症治療を考える素材をちょこっと提供。noteもあります https://note.com/twin1980

ASP

A Baker’s Dozen of Top Antimicrobial Stewardship Intervention Publications in 2018

Impact of a Prescriber-driven Antibiotic Time-out on Antibiotic Use in Hospitalized Patients

Cefazolin versus anti-staphylococcal penicillins for the treatment of methicillin-susceptible Staphylococcus aureus bloodstream infections in acutely-ill adult patients: results of a systematic review and meta-analysis

IDweek 2018 Poster : Antimicrobial Stewardship: Interventions to Improve Outcomes ②

Role of Early De-escalation of Antimicrobial Therapy on Risk of Clostridioides difficile Infection following Enterobacteriaceae Bloodstream Infections

IDweek 2018 Poster : Antimicrobial Stewardship: Interventions to Improve Outcomes ①